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Ventria Bioscience

From Wikipedia, the free encyclopedia
Ventria Bioscience
Company typePrivate company
IndustryBiotechnology
Founded1993
HeadquartersFort Collins, CO
Area served
United States
ProductsBioscience Products
Websitewww.ventria.com

Ventria Bioscience is a biotech company with a focus on human nutrition and human therapeutics. The company was established in 1993 in Colorado.[1] The company's core technology is a genetically modified crop-based protein production system (also called a "pharming" system or 'biopharming'[2]) called ExpressTec.[3][4][5] They have also made applications to grow rice with human genes.[2][6]

ExpressTec uses self-pollinating crops such as rice and barley to minimize the risk of gene flow normally associated with transgenic plants. Plant-produced proteins also offer advantages for cell culture and bioprocessing use because they replace animal derived components, which have become unpopular due to concerns about prion contamination.[citation needed]

Facilities

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Ventria's corporate headquarters is in Denver, Colorado, with additional facilities in Kansas. On September 29, 2006, Kansas officials announced an agreement to bring Ventria’s new bioprocessing facility to Junction City, Kansas. Kansas Governor Kathleen Sebelius was supportive of the agreement and was quoted as stating "I welcome Ventria Bioscience to Kansas and look forward to their contributions to the health of children worldwide."[7] The effort to attract Ventria to Kansas involved a number of players, including Governor Kathleen Sebelius, Secretary of Agriculture Adrian Polansky, The Kansas Department of Commerce, Junction City and Geary County, Kansas Technology Enterprise Corporation (KTEC), KansasBIO, Kansas State University, and Kansas Farm Bureau.

Divisions and Subsidiaries

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In 2009, Ventria Bioscience launched InVitria, a division focused on developing and commercializing animal-free cell culture supplements and reagents for the biotechnology and life sciences industries. InVitria's products, including recombinant proteins like human albumin and lactoferrin, are designed to replace animal-derived components in cell culture media. These products are used in various applications, such as cellular therapy, vaccines, medical devices, and regenerative medicine[8], providing more consistent, ethical, and safe alternatives for research and production in the biopharmaceutical field.[3]

Markets and products

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Human health, cell culture and biomanufacturing, and zoonotic disease are the three targeted markets for Ventria's products.[9]

As of 2012 Ventria is developing six therapeutic products:

The company offers contract biomanufacturing services using its ExpressTec platform, and, through its subsidiary InVitria, sells a line of its proteins that it manufactures for the life sciences research market.[16]

The company has conducted research in the field of zoonotic disease, specifically in lyme disease and rabies, with a goal of developing vaccines and offers some its recombinant proteins to life sciences researchers under a program called BioShare.[17]

Funding

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The company has been the recipient of grants and funding from organisations including the Bill & Melinda Gates Foundation, to develop their ExpressTec system.[3]

See also

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References

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  1. ^ Bloomberg BusinessWeek - Ventria Bioscience, Inc.
  2. ^ a b "'Biopharming' is back, report finds". NBC News. 2004-06-02. Retrieved 2024-07-19.
  3. ^ a b c "InVitria Announces New Media Formulation Service". Lab Manager. 2017-11-09. Retrieved 2024-07-19.
  4. ^ "Ventria Bioscience Wins Exclusion Order Against Infringing and Mislabled Products From Wuhan Healthgen". BusinessWire. 2022-09-14. Retrieved 2024-07-19.
  5. ^ Gilbert, Annelise (2023-10-03). "Ventria Defeats Wuhan Healthgen Challenge to Cell Culture Patent". news.bloomberglaw.com. Retrieved 2024-07-19.
  6. ^ "Rice with human genes to be grown in US". New Scientist. 2007-03-07. Retrieved 2024-07-19.
  7. ^ "Kansas Bio" (PDF).
  8. ^ Alfano, Randall; Youngblood, Bradford A; Zhang, Deshui; Huang, Ning; MacDonald, Clinton C (2014-05-01). "Human leukemia inhibitory factor produced by the ExpressTec method from rice (Oryza sativa L.) is active in human neural stem cells and mouse induced pluripotent stem cells". Bioengineered. 5 (3): 180–185. doi:10.4161/bioe.28996. ISSN 2165-5979. PMC 4101010. PMID 24776984.
  9. ^ "Ventria Bioscience Invited to Present ExpressTec (TM) at the 4th International Plant-Based Vaccines & Antibodies Conference". www.biotechnewswire.ai. 2011-06-06. Retrieved 2024-07-19.
  10. ^ Ventria VEN100 page
  11. ^ Ventria VEN101 page
  12. ^ Ventria VEN120 page
  13. ^ Ventria VEN130 page
  14. ^ Ventria VEN140 information on pipeline page
  15. ^ Ventria VEN200 page
  16. ^ InVitria Official Website
  17. ^ "BioShare | Research Collaborations with Ventria Bioscience".
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